Publications From The Santos Lab
Hypertranscription: the invisible hand in stem cell biology
Authors: Kim YK, Collignon E, Martin SB, Ramalho-Santos M.
Reference: Trends in Genetics, 2024, https://doi.org/10.1016/j.tig.2024.08.005
m6A RNA methylation orchestrates transcriptional dormancy during paused pluripotency
Authors: Collignon E, Cho B, Furlan G, Fothergill-Robinson J, Martin SB, McClymont SA, Ross RL, Limbach PA, Ramalho-Santos M.
Reference: Nature Cell Biology, 2023, https://doi.org/10.1038/s41556-023-01212-x
Colorectal Cancer Cells Enter a Diapause-like DTP State to Survive Chemotherapy
Authors: Rehman AK, Haynes J, Collignon E, Brown KR, Wang Y, Nixon AML, Bruce JP, Wintersinger JA, Mer AS, Lo EBL, Leung C, Lima-Fernandes E, Pedley NM, Soares F, McGibbon S, He HH, Pollet A, Pugh TJ, Haibe-Kains B, Morris Q, Ramalho-Santos M, Goyal S, Moffat J, O'Brien CA
Reference :Cell. 2021 Jan 7; 184(1):226-242.
PMID: 33417860
The Transcriptionally Permissive Chromatin State of Embryonic Stem Cells Is Acutely Tuned to Translational Output.
Authors: Bulut-Karslioglu A, Macrae TA, Oses-Prieto JA, Covarrubias S, Percharde M, Ku G, Diaz A, McManus MT, Burlingame AL, Ramalho-Santos M.
Reference: Cell Stem Cell. 2018 Mar 1;22(3):369-383.e8. doi: 10.1016/j.stem.2018.02.004.
PMID: 29499153
Inhibition of mTOR induces a paused pluripotent state.
Authors: Bulut-Karslioglu A, Biechele S, Jin H, Macrae TA, Hejna M, Gertsenstein M, Song JS, Ramalho-Santos M.
Reference: Nature. 2016 Dec 1;540(7631):119-123. doi: 10.1038/nature20578. Epub 2016 Nov 23.
PMID: 27880763