Publications From The Santos Lab

Nodal/Smad2 signaling sustains developmental pausing by repressing Pparg-mediated lipid metabolism
Authors: Furlan G, Martin SB, Cho B, McClymont SA, Robertson EJ, Colligon E, Ramalho-Santos M
Reference: bioRxiv, 2025.09.08.674904; doi: 10.1101/2025.09.08.674904

CHD1 is a synthetic lethal vulnerability in MYC-driven breast cancer
Authors: Cho B, Furlan G, Lin P, Shen M, Mittal K, Mazzanti A, Penn L, Ramalho-Santos M.
Reference: bioRxiv, 2025.08.14.670376; doi: 10.1101/2025.08.14.670376

Alpha satellite RNA marks the perinucleolar compartment and represses ribosomal RNA expression in naïve human embryonic stem cells
Authors: Mittal K, Ataei L, Ramalho-Santos M.
Reference: bioRxiv, 2025.07.11.664446; doi: 10.1101/2025.07.11.664446

20 years of stemness: From stem cells to hypertranscription and back
Authors: Kim YK, Ramalho-Santos M.
Reference: Stem Cell Reports, 2025 Mar 11;20(3):102406. doi: /10.1016/j.stemcr.2025.102406
PMID: 39919752